Novel serological and molecular tools for malaria surveillance and intervention

As malaria transmission continues to decline, even the most sensitive methods for determining prevalence via detection of the parasite become inefficient for risk stratification and informing programmatic interventions. In addition, the need to identify individuals at risk of Plasmodium vivax relapse from hypnozoites increases.

Validated markers of recent exposure to Plasmodium spp. may be able to play an important role, particularly rapidly advancing technologies for quantitative point-of-care testing.